Asymptotic analysis of noisy fitness maximization, applied to metabolism and growth

We consider a population dynamics model coupling cell growth to a diffusion in the space of metabolic phenotypes as it can be obtained from realistic constraints-based modelling. In the asymptotic regime of slow diffusion, that coincides with the relevant experimental range, the resulting non-linear Fokker-Planck equation is solved for the steady state in the WKB approximation that maps it into the ground state of a quantum particle in an Airy potential plus a centrifugal term. We retrieve scaling laws for growth rate fluctuations and time response with respect to the distance from the maximum growth rate suggesting that suboptimal populations can have a faster response to perturbations.Comment: 24 pages, 6 figure

Bethe Ansatz and the Spectral Theory of affine Lie algebra--valued connections II. The non simply--laced case

We assess the ODE/IM correspondence for the quantum $\mathfrak{g}$-KdV model, for a non-simply laced Lie algebra $\mathfrak{g}$. This is done by studying a meromorphic connection with values in the Langlands dual algebra of the affine Lie algebra ${\mathfrak{g}}^{(1)}$, and constructing the relevant $\Psi$-system among subdominant solutions. We then use the $\Psi$-system to prove that the generalized spectral determinants satisfy the Bethe Ansatz equations of the quantum $\mathfrak{g}$-KdV model. We also consider generalized Airy functions for twisted Kac--Moody algebras and we construct new explicit solutions to the Bethe Ansatz equations. The paper is a continuation of our previous work on the ODE/IM correspondence for simply-laced Lie algebras.Comment: 37 pages, 1 figure. Continuation of arXiv:1501.07421. Minor change in the title. New subsection 5.1 on the action of the Weyl group on the Bethe Ansatz solution